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Guanidine thiocyanate is a colorless crystal or white powder. It is easily soluble in water, its solubility in water can reach 4M, and it can dissolve at 1420g / L at 20 ℃. Soluble in ethanol. The melting point was 118 ℃. Light sensitive. Irritating. The density is 1.29 g / cm3 (20℃). Guanidine thiocyanate is a decoupling agent. It is a strong class of protein denaturants that can dissolve proteins and cause the protein secondary structure to disappear, cell structure to be degraded, and nuclear proteins to be rapidly separated from nucleic acids. It is mainly used to extract DNA and RNA.

product Name	Guanidine thiocyanate
Synonyms	Guanidine isothiocyanate; Guanidinium Isothiocyanate; Thiocyanic acid, compd. with guanidine (1:1); GTC; guanidine thiocyanate (1:1); 2-(cyanosulfanyl)guanidine
Molecular Formula	C2H4N4S
Molecular Weight	116.145
InChI	InChI=1/C2H4N4S/c3-1-7-6-2(4)5/h(H4,4,5,6)
CAS Registry Number	593-84-0
EINECS	209-812-1
Molecular Structure
Density	1.57g/cm3
Melting point	118-122℃
Boiling point	290.6°C at 760 mmHg
Refractive index	1.694
Flash point	129.5°C
Vapour Pressur	0.00206mmHg at 25°C